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Efficacy comparison among different vaccination doses of AI inactived oilemulsion vaccine
WEN Zhifen1, CHEN Ruiai2, TANG
Manhua2, ZHAO Mingqiu2
(1. College of Animal Science, South China Agricultural University, Guangzhou 510642,China; 2. Guangdong Wen’s Foodstuffs Group Limited Company, Xinxing 527439,China) |
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Abstract: Forty serven SPF chickens aged 28 days were divided into 4 groups. There were 12 chickens in each of the first 3 groups and vaccinated by intramuscular injection with inactivated oilemulsion vaccine against AIV at dosage of
0.1mL per chicken, 0.3mL per chicken and 0.5mL per chicken respectively. There were 11 chickens in the 4th group as blank control. Sera of all chickens were collected at the 1st, 2nd, 3rd, 5th, 7th and 8th week postvaccination for HI test use. All chickens were challenged with AIVH9N2 at a dosage of
0.2mL per chicken at the 3rd week postvaccination. It was showed by the results that vaccinated efficacy at a dosage of
0.5mL per chicken was better than that at a dosage of 0.1 or 0.3mL per chicken, and the AIVH9N2 challenged was not a highpathogenicity virus and can’t induce death to all of the chickens.
Key words: avian influenza; inactivated vaccine; vaccinated efficacy |
