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剑尾鱼感染嗜水气单胞菌的动态病理变化观察

杜雄伟1, 于 博, 李 叶2, 常藕琴, 吴淑勤3, 石存斌3

(1. 中山大学 实验动物中心, 广东 广州 510080; 2. 华南农业大学 兽医学院, 广东 广州 510642;
3. 中国水产科学研究院 珠江水产研究所, 广东 广州 510380)

摘要: 对剑尾鱼感染嗜水气单胞菌的病理变化进行了全面细致的观察。结果显示:剑尾鱼感染发病呈急性过程,感染后10~15h为发病死亡高峰期;病理组织学变化以全身溶血性贫血和广泛的组织细胞变性、坏死为主;感染发病死亡时间主要集中在5~24h,感染部位和鳃最先受到损伤,最终因各器官结构破坏、功能衰竭和窒息而亡。

关键词: 剑尾鱼; 嗜水气单胞菌; 病理变化

中图分类号:S 941.4  文献标识码:文章编号:1000-6419(2004)10-0022-04

Observation on dynamic pathological changes of Xiphophorus 
helleri infected with Aeromonas hydrophila

DU Xiongwei1, YU Bo2, LI Ye2, CHANG Ouqin3, WU Shuqin3, SHI Cunbin3

(1. Center for Laboratory Animals, Sun Yatsen University, Guangzhou 510080, China;
2. College of Veterinary Medicine, South China Agricultural University, Cuangzhou 510642, China;
3. Pearl River Fishery Research Institute,Chinese Academy of Fishery Sciences, 
Guangzhou 510380,China)

Abstract:Pathological changes of Xiphophorus helleri infected with Aeromonas hydrophila were observed completely in this study. The results were as follows. Infection outbreak was an impatient process, and the peak time of death was at 10-15h postinfection. Histopathological changes were characterized by general hemolytic anemia, extensive cellular degeneration and necrosis. Cardinal symptoms and pathological changes came about from 5 to 24h postinfection. Injection sites and gills were damaged initially. Finally the infected animals died because of organic structure breakage, function adynamia and asphxia.

Key words: Xiphophorus helleri; Aeromonas hydrophila; pathological change

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