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植物雌激素生殖发育毒性的研究进展
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武振龙1，2， 杨 鹰1， 陈 越2， 夏国良2 ， 张荣庆1
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(1. 清华大学 生物科学与技术系， 北京 100084； 2. 中国农业大学 生物学院， 北京 100094)
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摘要：
阐述了植物雌激素的分类、作用机理及其对动物及人类生殖发育毒性的研究进展，旨在通过探讨植物雌激素对动物体的拟激素作用，证实其对人类生殖健康的影响。 |
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关键词：
植物雌激素； 生殖毒性； 发育毒性 |
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中图分类号：R 996.2：S 814.1 文献标识码：
B 文章编号：1000-6419(2005)01-0074-07 |
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Progress of phytoestrogen on reproductive and developmental toxicology |
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WU Zhenlong1,2， YANG
Ying1， CHEN Yue2， XIA Guoliang2， ZHANG
Rongqing1 |
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(1. Department of Biological Science and Technology, Tsinghua University, Beijing 100084,China;
2.Department of Biological Science,China Agricultural University, Beijing 100094,China) |
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Abstract: Phytoestrogens are plant compounds that are structurally and functionally similar to estrogen and have the ability to bind estrogen receptors. Studies have demonstrated that animals exposure to phytoestrogen has the potential to cause developmental alteration to the endocrine system and reproductive system. This article introduced the current progress on the reproductive and developmental toxicology in rodent, sheep, primates and human. |
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Key words: phytoestrogen; reproductive toxicology; developmental toxicology |
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