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Nitazoxanide 干混悬剂处方研究及稳定性初步考察

尚 炜,薛飞群

(中国农业科学院 上海家畜寄生虫病研究所 农业部动物寄生虫学重点开放实验室,上海 200232)

摘要: 以沉降体积比、再分散性、pH值为考察指标,采用正交设计试验对Nitazoxanide干混悬剂处方进行筛选,并考察了优选处方制剂的流体性能、粒径分布及稳定性。
关键词: NTZ干混悬剂;处方;稳定性
中图分类号:S 859.54  文献标识码:文章编号:1000-6419(2005)S1-0055-04

Study on preparation and stability of NTZ for dry suspension

SHANG Wei,XUE Fei-qun

(Key Laboratory for Animal Parasitology,Ministry of Agriculture/Shanghai Institute of Domestic Animal Parasitology,Chinese Academy of Agricultural Sciences,Shanghai 200232,China)

Abstract: In order to select an optimized recipe of NTZ for dry suspension ,an orthogonal design ex-periment was carried out by determination of the ratio setting volume,redispersibility and pH value of the suspensions. The hydromechanical characters,distribution of granularity and stability were also as-sessed.

Key words: NTZ for dry suspension;optimized recipe;stability

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