| |
|
 |
|
|
|
加味玉屏风散对鸡红细胞免疫和自由基的影响
|
|
|
|
杨鸿1,2 ，陈杖榴1，邓桦2，何永明2
|
|
|
|
(1. 华南农业大学 兽医学院，广东 广州510642；
2. 佛山科学技术学院 动物医学系，广东 佛山528231）
|
|
|
|
摘要：
|
|
将300只1日龄艾维茵雏鸡随机分为5组。Ⅰ组为加味玉屏风散（YPFP）+ 环磷酰胺（CY），Ⅱ组为左旋咪唑+CY，Ⅲ组为YPFP，Ⅳ组为CY，Ⅴ组为正常对照组。检测雏鸡红细胞免疫功能、全血GSHPx活性、血浆SOD活性、血浆MDA浓度及体重。结果显示，YPFP能显著提高正常雏鸡RBCCR1R，增强GSHPx和SOD活性，降低血浆MDA的浓度，并能拮抗CY诱导的雏鸡RBCCR1R降低、RBCICR升高、GSHPx和SOD活性下降以及MDA浓度升高。相关研究发现，血浆SOD活性与RBCCR1R呈正相关，与RBCICR呈负相关；而MDA浓度与RBCCR1R呈负相关，与RBCICR呈正相关。试验证明，YPFP能明显增强雏鸡红细胞的免疫功能，提高雏鸡体内抗氧化酶活性，具有抗自由基损伤作用；YPFP能使雏鸡生长加快，体重增加。 |
|
关键词：
|
|
加味玉屏风散； 雏鸡； 红细胞免疫； 自由基 |
|
中图分类号：S 853.1 文献标识码：
A 文章编号：1673-4696(2006)01-0070-04 |
|
|
Effect of Plus Yupingfeng Powder on immune function of
red blood cell and oxygen free radicals in chickens |
|
|
|
YANG Hong1,2，CHEN
Zhangliu1，DENG Hua2，HE
Yongming2 |
|
|
|
(1. College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642,China;
2. Department of Veterinary Medicine, Foshan University, Foshan 528231,China) |
|
|
Abstract: To investigate the effect of Plus Yupingfeng Powder(YPFP) on immune function of red blood cell (RBC) and oxygen free radical(OFR) in chickens and to study correlation between them，300 onedayold chickens were divided randomly into 5 groups of 60 each. Chickens in different group were given different medicine：GroupⅠ was given YPFP and cyclophosphamide(CY), GroupⅡ was given levamisole and CY, GroupⅢ was given YPFP, GroupⅣ was given CY, and GroupⅤ was given physiological saline solution. Then the immune function of RBC, activity of blood GSHPx and plasma SOD, content of plasma MDA, and body weight were examined. YPFP could increase ratio of RBCCR1 rosette，enhance the activity of blood GSHPx and plasma SOD，and reduce the content of plasma MDA significantly. Cyclophosphamide could induce RBCCR1 rosette ratio to decrease and RBCIC rosette ratio to increase，the activity of blood GSHPx and plasma SOD to decrease，and the content of plasma MDA to increase. But all the above changes could be antagonized by YPFP. Results of correlation study indicated that the activity of plasma SOD was positively related with the RBCCR1R, but negatively related with the RBCICR, and the content of plasma MDA was negatively related with RBCCR1R, but was positively related with RBCICR. The results showed that YPFP can increase the immune function of RBC, enhance the activity of antioxidant enzymes, resist damage of the redundant OFR, and enhance growth of chickens, significantly. |
|
|
|
Key words: Plus Yupingfeng Powder（YPFP）; chicken; red cell immune function; oxygen free radical |
|
|
|
|
|
《中国兽医科学》 ©
版权所有
Chinese Veterinary Science
zgsykx@zgsykx.com |
|
