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雏鸭胸腺生长指标的动态观测及组织学观察

方静,崔恒敏,彭西,何敏

(四川农业大学 动物科学技术学院,四川 雅安625000)

摘要:  
通过对1~49日龄雏鸭胸腺发育的组织学观察及胸腺重量、胸腺指数和外周血T淋巴细胞α-醋酸萘酯酶阳性率(ANAE+)的测定,研究了雏鸭胸腺的生长及组织发育规律。结果显示,胸腺重量随日龄增长逐渐增加;胸腺指数在28日龄时达最高;1~28日龄时外周血T淋巴细胞ANAE+上升幅度较大;21~28日龄时胸腺小叶数量增多,并显著增大;28日龄时皮质部主要为小淋巴细胞;胸腺小体有3种形态。表明,雏鸭在1~14日龄时胸腺生长较缓慢,21~28日龄时生长十分迅速,28日龄时胸腺中大部分T淋巴细胞已发育成熟,35~49日龄时胸腺发育已趋于稳定;胸腺小体是具有高度活性的结构,与清除退变上皮有关。
关键词:  
雏鸭;胸腺发育;T淋巴细胞;胸腺小体
中图分类号:S 852.1  文献标识码:文章编号:1673-4696(2006)05-0401-05

Dynamic measurement of growth indexes and histological 
observation of thymus of ducklings

FANG Jing,CUI Heng-min,PENG Xi,HE Min

(College of Animal Science and Technology, Sichuan Agricultural University,Ya’an 625000,China)

Abstract: By using HE method and measuring weight and growth index of thymus and rate of ANAE+T lymphocytes in peripheral blood, the growth and histological development of thymus of ducklings were studied from 1 to 49 days-old. The weight of thymus increased as the ducklings grew. The highest growth index of thymus was obtained for ducklings of 28 days-old. The rate of ANAE+T lymphocytes in peripheral blood increased obviously from 1 to 28 days-old. The numbers of thymic lobules with small-sized lymphocytes predominantly in the cortex on 28 days-old increased obviously. There were three types of thymic corpuscles. Results showed that the duckling thymus developed slowly from 1 to 14 days-old, quickly from 21 to 28 days-old and steadily from 35 to 49 days-old. On 28 days-old, most T-lymphocytes reached their maturation. The thymic corpuscles might be the sign of activation and is related with elimination of the degenerating cells.

Key words: duckling; development of thymus; T-lymphocyte; thymic corpuscle

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