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病毒干扰抗原递呈途径和细胞杀伤作用的研究进展

马中军1,马志宏1,2,沈小燕3

(1.甘肃省畜牧兽医研究所,甘肃 平凉744000; 2.甘肃农业大学 动物医学院,甘肃 兰州730070; 
3.中国农业科学院 兰州兽医研究所,甘肃 兰州730046)

摘要:  
从病毒干扰宿主免疫细胞对病毒抗原的摄取、递呈和杀伤等方面阐述了病毒抗感染免疫应答的研究进展。探讨了病毒感染宿主后,病毒对机体细胞免疫应答的抑制、对各种免疫杀伤细胞功能的阻断以及在宿主体内延续感染的机制。
关键词:  
病毒;抗原递呈;杀伤细胞;免疫应答
中图分类号:S 852.65 文献标识码:文章编号:1673-4696(2006)06-0512-03

Advances in virus interfering with presenting routes of 
antigen and killing functions of immunocytes

MA Zhong-jun1,MA Zhi-hong1,2,SHEN Xiao-yan3

(1.Gansu Institute of Animal Science and Veterinary Medicine, Pingliang 744000, China; 
2.College of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China; 
3.Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China)

Abstract: The research advances were reviewed on the aspects of virus’s interfering with immunocyte intaking, presenting and killing antigen of the virus. Mechanisms of the virus resisting to host immunolo-gical response, blocking functions of various killer cells and further infection in the host were discussed.

Key words: virus; antigen presenting; killer cell; immunological response

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