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病毒干扰抗原递呈途径和细胞杀伤作用的研究进展
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马中军1,马志宏1,2,沈小燕3
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(1.甘肃省畜牧兽医研究所,甘肃 平凉744000; 2.甘肃农业大学 动物医学院,甘肃 兰州730070;
3.中国农业科学院 兰州兽医研究所,甘肃 兰州730046)
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摘要:
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从病毒干扰宿主免疫细胞对病毒抗原的摄取、递呈和杀伤等方面阐述了病毒抗感染免疫应答的研究进展。探讨了病毒感染宿主后,病毒对机体细胞免疫应答的抑制、对各种免疫杀伤细胞功能的阻断以及在宿主体内延续感染的机制。 |
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关键词:
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病毒;抗原递呈;杀伤细胞;免疫应答 |
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中图分类号:S 852.65 文献标识码:
A 文章编号:1673-4696(2006)06-0512-03 |
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Advances in virus interfering with presenting routes of
antigen and killing functions of immunocytes |
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MA Zhong-jun1,MA
Zhi-hong1,2,SHEN Xiao-yan3 |
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(1.Gansu Institute of Animal Science and Veterinary Medicine, Pingliang 744000, China;
2.College of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China;
3.Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China) |
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Abstract: The research advances were reviewed on the aspects of virus’s interfering with immunocyte intaking, presenting and killing antigen of the virus. Mechanisms of the virus resisting to host immunolo-gical response, blocking functions of various killer cells and further infection in the host were discussed. |
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Key words: virus; antigen presenting; killer cell; immunological response |
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