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利用转基因植物生产口蹄疫可饲疫苗的
研究进展与前景
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呼格吉乐图，吴应积，旭日干
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（内蒙古大学 生命科学学院 哺乳动物生殖生物学及生物技术教育部重点实验室，内蒙古 呼和浩特 010023）
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摘要：
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从口蹄疫可饲疫苗的研究概况、生产技术要点、优缺点及需要改进的问题几方面阐述了利用植物反应器生产口蹄疫可饲疫苗的研究前景。综述了口蹄疫可饲疫苗的研究进展，介绍了利用植物反应器生产口蹄疫可饲疫苗的技术要点，包括在口蹄疫病毒遗传转化质粒载体系统中最常用的农杆菌介导法，提出了生产口蹄疫可饲疫苗需要改进的技术问题。 |
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关键词：
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口蹄疫病毒；VP1基因；可饲疫苗；转基因植物 |
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中图分类号：S 855.3 文献标识码：
A 文章编号：1673-4696(2006)09-0767-06 |
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Research advance in edible vaccines against
foot-and-mouth disease by using transgenic plants |
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Hugjiltu,WU Ying-ji,Shorgan |
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(Key Laboratory of Reproductive Biology of Mammals and Biotechnology,Ministry of Education/
College of Life Sciences, Nei Monggol University, Hohhot 010023, China) |
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Abstract: Prospect of producting edible vaccines against foot-and-mouth disease by using transgenic plants was elucidated on research facts, key points of producing technology, advantages and defectives or problems for improvement. Research progress on edible vaccines against foot-and-mouth disease was reviewed. Key techniques for producing edible vaccines against foot-and-mouth disease by using transgenic plants were summarised, including agrobacterium-mediated transformation which was commonly used in plasmid vectors of hereditary changes. The technical problems for improving the production of edible vaccines were discussed. |
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Key words: foot-and-mouth disease virus; VP1 gene; edible vaccine; transgenic plant |
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