|
|
|
大肠杆菌耐热肠毒素b及其致动物腹泻的机理
|
|
|
|
尤建嵩，牛冬燕，崔乃忠，孙永欣，金礼吉，徐永平
|
|
|
|
(大连理工大学 环境与生命学院 生物科学与工程系，辽宁 大连116024)
|
|
|
|
摘要：
|
|
介绍了大肠杆菌耐热肠毒素b（STb）的编码基因、理化性质、免疫学特征、分泌特征、毒性相关氨基酸残基、空间结构、膜受体以及STb致动物腹泻的机理。认为STb是一种十分重要的肠毒素，应进一步加强对STb及其致腹泻机理的研究。 |
|
关键词：
|
|
产肠毒素大肠杆菌；耐热肠毒素b；腹泻；机理 |
|
中图分类号：S 852.612 文献标识码：
A 文章编号：1673-4696(2006)10-0847-05 |
|
|
Escherichia coli heat-stable enterotoxin b(STb) and its
mechanism causing diarrhea in animals |
|
|
|
YOU Jian-song, NIU Dong-yan, CUI Nai-zhong, SUN Yong-xin, JIN Li-ji, XU Yong-ping |
|
|
|
(Department of Bioscience and Biotechnology, School of Environmental and Biological Science
and Technology, Dalian University of Technology, Dalian 116024, China) |
|
|
Abstract: Current knowledge and research advances in E.coli heat-stable enterotoxin b (STb) were reviewed from the perspective of its genetic, chemical and physical features, immunogenicity, secretion, residues related to toxicity, structure, receptor, and its mechanism causing diarrhea. STb is considered a very important enterotoxin due to its highly prevalence in ETEC strains isolated from piglets with diarrhea and could cause considerable losses to livestock industry. Therefore, the researchers should pay more attention to study STb and its action mechanism in order to reduce the economic losses caused by ETEC. |
|
|
|
Key words: enterotoxigenic Escherichia coli; heat-stable enterotoxin b; diarrhea; mechanism |
|
|
|
|
|
《中国兽医科学》 ©
版权所有
Chinese Veterinary Science
zgsykx@zgsykx.com |
