|
|
|
高铜对雏鸭肝影响的病理学观察
|
|
|
|
赵丽，崔恒敏，杨帆，彭西，邓俊良
|
|
|
|
（四川农业大学 动物科技学院，四川 雅安625014）
|
|
|
|
摘要：
|
|
将360只1日龄天府肉鸭随机分为6组，分别喂以对照日粮（Cu 8mg/kg）和高铜日粮（Ⅰ组：Cu 100mg/kg；Ⅱ组：Cu 200mg/kg；Ⅲ组：Cu 400mg/kg；Ⅳ组：Cu 600mg/kg；Ⅴ组：Cu 800mg/kg）6周，研究日粮铜添加水平对雏鸭肝及其相关生化指标的影响。结果显示，Ⅱ组、Ⅲ组、Ⅳ组、Ⅴ组雏鸭肝出现不同程度的病理损伤，肝细胞颗粒变性、空泡变性。Ⅳ组、Ⅴ组肝铜含量和血清铜含量均显著高于对照组（P<0.01）。Ⅲ组、Ⅳ组和Ⅴ组血清丙氨酸氨基转移酶、天门冬氨酸氨基转移酶活性显著升高（P<0.01）。结果表明，日粮铜含量达400～800mg/kg即可引起肝的病理损伤。 |
|
关键词：
|
|
雏鸭；高铜；肝；病理变化；生化指标 |
|
中图分类号：S 852.35 文献标识码：
A 文章编号：1673-4696(2007)11-0990-04 |
|
|
Pathological evaluations of effect of high dietary copper intake on liver
in ducklings |
|
|
|
ZHAO Li,CUI Heng-min，YANG Fan,PENG Xi,DENG Jun-lian |
|
|
|
（College of Animal Science and Veterinary Medicine,Sichuan Agricultural University,Ya’an 625014，China） |
|
|
Abstract: Effect of high dietary copper intakes on the liver was evaluated in infant ducklings.Ducklings (60/group) one day of age at the start of dosing were fed a diet containing 8(Control),100 (GroupⅠ),200 (GroupⅡ),400 (Group Ⅲ),600 (GroupⅣ),or 800 (GroupⅤ) mg/kg per day for 6 weeks.All ducklings were sacrificed at the end of the treatment for pathologic observation and liver functional enzyme levels were determined.Granular and vacuolar hepatocytes were observed in GroupsⅡ，Ⅲ,Ⅳ and Ⅴ.Liver and serum copper contents in groups Ⅳ and Ⅴ were statistically significantly higher than that in the control group（P<0.01）.Activities of serum glutamic pyruvic transminase and glutamic oxaloacetic transaminase in Groups Ⅲ,Ⅳ and Ⅴwere much higher than that in the control group (P<0.01).The above results indicated that the duckling liver was damaged when dietary intake of copper in reached 400-800mg/kg per day. |
|
|
|
Key words: duckling;high copper;liver;lesions;biochemical index |
|
|
|
|
|
《中国兽医科学》 ©
版权所有
Chinese Veterinary Science
zgsykx@zgsykx.com |
