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疱疹病毒UL34基因及其编码蛋白的研究进展
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钟小容1,程安春1,2,汪铭书1,2,陈孝跃1
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(1.四川农业大学 动物医学院 禽病防治研究中心,四川 雅安625014;
2.动物疾病与人类健康四川省重点实验室,四川 雅安625014)
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摘要:
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论述了疱疹病毒UL34基因的序列特点、编码蛋白结构特点、基本功能以及它与UL31蛋白、Us3蛋白、动力蛋白、核纤层蛋白的相互作用。表明,UL34基因对病毒的早期包装、成熟和出芽以及对UL31蛋白和核纤层蛋白在感染细胞中的正确定位都具有重要作用。 |
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关键词:
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疱疹病毒;UL34基因;编码蛋白 |
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中图分类号:S 852.659.1 文献标识码:
A 文章编号:1673-4696(2007)12-1099-05 |
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Advance in UL34 gene of herpesvirus and its encoding protein |
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ZHONG Xiao-rong1,CHENG An-chun1,2,WANG
Ming-shu1,2,CHEN Xiao-yue1 |
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(1.Research Center for Avian Diseases,College of Veterinary Medicine,Sichuan Agricultural University,Ya’an
625014,China;2.Key Laboratory of Animal Diseases and Human Health of Sichuan Province,Ya’an 625014,China) |
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Abstract: The advance in UL34 gene of herpesvirus was reviewed on gene’s characteristic and the construction features,basic functions of the encoding protein and its interactions with UL31 protein,US3 protein,dynein protein and lamin protein.Then,the important roles of the gene in viral primary envelopment,mature and budding,proper location of the UL31 protein and lamin protein in cells infected with the virus were pointed out. |
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Key words: herpesvirus;UL34 gene;encoding protein |
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